A team of scientists in the UK and Italy has completed new research into motor neuron disease that could spark the development of new treatments. By comparing mice with fast progressing ALS (amyotrophic lateral sclerosis), the most common form to mice with the slow progressing form, they found some clues that could help develop new drugs to slow the disease.
ALS accounts for between 60-70% of all cases of motor neuron disease (MND), a serious and incurable disease where nerves in the spine and brain that control movement (motor function) gradually stop working and die. Patients in the later stages of disease may become totally paralyzed and completely lose their ability to walk, talk, eat and breathe.
The team, from the UK's University of Sheffield's Institute for Translational Neuroscience (SITraN) and the Mario Negri Institute for Pharmacological Research in Milan, Italy, report their findings in the journal Brain.
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