Published by Amy Fernandes
Angelina Jolie’s recent double mastectomy has highlighted the debate on breast cancer. The fact remains, however, that the number of new cases of breast cancer has jumped dramatically worldwide, from about 640,000 in 1980 to more than 1.6 million in 2010, according to the University of Washington researchers’ report. One of the many causes for fatalities is the high toxicity of the treatment and the current disability of affected cells to absorb the dosage.
As for the triple negative breast cancer sufferers this becomes even harder to treat. These breast cancers do not respond to hormonal therapy and require more than one chemotherapy drug for treatment. Unfortunately, such combination chemotherapy increases the toxicity of the treatment, often limiting the extent of therapy tolerated. Further, many women with triple negative breast cancer develop “multidrug resistance” which makes them insensitive to anticancer drugs similar to the concept of antibiotic resistance.
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