Showing posts with label Toxic. Show all posts
Showing posts with label Toxic. Show all posts

Wednesday, June 17, 2009

Researchers uncover how nanoparticles may damage lungs

Posted by Neill Abayon

HONG KONG (Reuters) - Researchers in China appear to have uncovered how nanoparticles which are used in medicine for diagnosis and delivering drugs may cause lung damage.

Nanotechnology, or the science of the extremely tiny, is an important industry. One nanometer is one-billionth of a meter.

Apart from medicine, it is used in products like sporting goods, cosmetics, tires and electronics and has a projected annual market of around US$1 trillion by 2015.

However, concerns are growing that it may have toxic effects, particularly to the lungs. But it has never been clear how the damage is caused.

In an article published in the Journal of Molecular Cell Biology, the Chinese experts said a class of nanoparticles used in medicine, ployamidoamine dendrimers (PAMAMs), may cause lung damage by triggering a type of programed cell death known as autophagic cell death.

In experiments, they observed how several types of PAMAMs killed human lung cells but found no evidence that the cells were dying by apoptosis, a natural and common type of cell death.

View the full article here.






Tuesday, July 15, 2008

Toxic chemical levels finally dropping in Arctic food animals, new study shows

Posted by Neill Abayon

After decades of concern about southern pollutants poisoning traditional foods that northern aboriginals depend on, a new government study suggests levels of toxic chemicals in a wide range of animals across the Arctic are finally dropping.

The study, the first large-scale attempt in a decade to measure contaminants in common Arctic food animals, found carcinogens such as PCBs and other toxins derived from pesticides sprayed in the south have largely levelled off or have begun declining.

"Organochlorines, like DDT or chlordane or toxaphene or industrial chemicals like PCB, are declining," said project leader Laurie Chan of the University of Northern British Columbia. "That's good news."

However, the study found that mercury, probably from the increasing use of coal in power generation around the globe, remains stubborn and is even rising in some animals.

Still, Chan said, the falling organochlorine levels are proof that international agreements on limiting the use of toxic chemicals can produce real improvements in food safety.

"It seems that the Stockholm Convention is having some effect," Chan said.

That convention - heavily pushed by Canada - came into effect in 2004 and limited the use of the so-called "dirty dozen" chemicals pushed into the Arctic and concentrated there by global air currents.

At one time, Canada's Inuit had some of the highest PCB levels in the world, up to 10 times the levels found in southern Canada. The chemical was even found in the breast milk of Inuit mothers.

A 2003 study found subtle but statistically significant nervous system and behavioural changes in Inuit babies that may be linked to PCBs.

But now, PCB levels in beluga, narwhal, walrus and ringed seal have fallen by an average of 43 per cent since 1997. Although it varies in different parts of the Arctic, the amount of the chemical that Inuivialuit or Inuit people are exposed to has dropped by an average of 20 per cent over the last decade.

Similarly, human exposure to toxaphene - an insecticide that can damage the lungs, nervous system and kidneys - has fallen an average of one-third across the Arctic.

The results from Chan's group, which are currently being prepared for publication in a scientific journal, echoed a smaller study released last fall.

That study found average PCB levels in the blood of pregnant women from 14 communities in the northwestern Northwest Territories fell 24 per cent between 2000 and 2007.

Mercury remains a problem. Levels of the toxic metal increased 42 per cent in ringed seal flesh, although the average exposure increase for humans was marginal.

"We don't see any decrease in mercury across the board," Chan said.

"The major source of mercury is air pollution, from coal-fired power generation. We know that is increasing all the time."

The study is good news for aboriginal people in the North, many whom still depend on food they harvest from the land and sea. A 2006 survey of 45 communities across the Canadian North suggested that between 20 and 30 per cent of the diet of aboriginal northerners consists of so-called country food.

Nutritionists say such foods are often healthier than the highly processed - and highly expensive - foods available in northern groceries.

Still, Chan acknowledges there's still more work to do. His research, for example, didn't include caribou, which many northerners eat on a near-daily basis.

A comprehensive health survey of all coastal Inuit communities is underway which will measure actual contaminant blood levels. That study, which is being done by researchers on the Coast Guard icebreaker CCG Amundsen, is complete for Nunavut and the results are expected next summer.

A similar survey in communities on the north coast of the Northwest Territories as well as Labrador will be conducted this summer.

Source:http://canadianpress.google.com

Friday, May 30, 2008

Toxic Fire Retardant Chemicals Found in Common Baby Products

Posted by Neill Abayon

Toxic fire retardant chemicals linked to cancer, birth defects, and neurological and other health problems are prevalent in common baby products, according to a study released today by national environmental group Friends of the Earth.

The study finds that these toxic chemicals, called halogenated fire retardants, appear in a high percentage of baby products, including portable cribs, strollers, car seats and infant carriers. Due to their prevalence in common household products, these chemicals have been found in breast milk and in children. Infants and children are especially vulnerable to the health effects of these chemicals as they impact development at critical stages of growth.